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What is Xifaxan?

Xifaxan and the generic alternative rifaximin are antibiotic medications used to fight bacterial infection in the intestines. It can be used to treat irritable bowel syndrome (IBS), travelers’ diarrhea and to lower the risk of decline in brain functions in adult with liver failure. Rifaximin is different to other antibiotics as it passes through your stomach into the intestines without being absorbed into the blood stream. The medication works by stopping the growth of the bacteria which cause diarrhea.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

• Xifaxan may be taken with or without food.
• When taking rifaximin for IBS, it is usually taken three times a day for two weeks.
• When taking rifaximin for travelers’ diarrhea, it is usually taken three times a day for three days.
• Use Xifaxan for the full prescribed amount of time even if your symptoms improve. Skipping doses may increase your risk of infection.
• Tell your doctor if your symptoms do not improve after 24-48 hours.

Make sure to tell your doctor and pharmacist:

• If you have any drug or other allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history especially of liver disease, bloody or watery diarrhea or diarrhea with a fever.
• If you are pregnant or breast feeding.

Also be aware that:

• Xifaxan should not be used if you are under 12.
• Xifacan may cause live bacterial vaccines to be less effective. Do not have any vaccinations while taking this medication unless advised to by a doctor.

Common Xifaxan side effects may include but are not limited to:

• Nausea or stomach pain.
• Excessive tiredness.
• Headache or dizziness.
• Joint pain or muscle tightening.

Contact your doctor if you experience any of the following side effects of Xifaxan:

• Watery or bloody diarrhea with stomach cramps and fever. This may occur during treatment or up to two months afterwards.
• Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

What should I do if I miss a dose of Xifaxan?

If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, then skip your missed dose.

What else is Xifaxan called?

Xifaxan is also known as Xifaxanta and Zaxine. Xifaxanta and Zaxine are not a generic alternatives but the same brand name medication with different names internationally. The generic alternative to Xifaxan is known as rifaximin.