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What is Soriatane?

Soriatane (acitretin) is a medication prescribed to treat severe psoriasis and other skin disorders. Acitretin is a retinoid which is a form of vitamin A. The medication works by allowing normal growth and development of your skin. Soriatane is not a cure for psoriasis and you may relapse once you stop taking this medication.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

• Soriatane should be taken with food.
• You may need frequent blood tests, medical tests or x-rays while taking acitretin.
• It can take 2-3 months before your symptoms improve. Your psoriasis may get even worse when you start taking acitretin. Continue to take the medication as directed and tell your doctor if your symptoms do not improve.
• You must never share this medication with anyone else, even if they have the same symptoms as you.

Make sure to tell your doctor and pharmacist:

• If you have any drug or other allergies.
• Which other prescription and non-prescription medications you currently take or if you have ever used etretinate (Tegison, Tigason).
• Your medical history especially of liver disease, kidney disease, high levels of triglycerides, heart disease, high cholesterol, diabetes, depression or phototherapy.
• If you have a habit of drinking large amounts of alcohol.

Also be aware that:

• Soriatane can cause severe birth defects and is only available to women who have two negative pregnancy tests and agree to use two methods of approved birth control. You will also need pregnancy tests every month while taking Soriatane and every three months for at least three years after your last dose. You may not be able to continue taking this medication if you miss a scheduled pregnancy test. Talk to your doctor for more information.
• Do not breast-feed while taking Soriatane.
• Do not drink alcohol while taking this medication and for two months after. Alcohol can cause acitretin to stay in your body for longer.

Common Soriatane side effects may include but are not limited to:

• Itching, scaling, redness, peeling or dry skin during the first few weeks.
• Dry eyes, eye irritation or a crusting of your eyelids.
• Dry mouth or chapped lids.
• Runny nose.
• Skin peeling on fingertips, palms or soles of your feet.
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• Hair loss.
• Thirst or taste changes.
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Contact your doctor if you experience any of the following side effects of Soriatane:

• Mental or mood changes such as depression, irritability, aggressiveness, violent behavior or suicidal thoughts. These may occur even after stopping this medication.
• Decreased night vision.
• Persistent lower abdominal pain. This may be a sign of pancreatitis.
• Fever or chills.
• Dizziness.
• Pain, weakness or tenderness in your muscles.
• Difficulty moving.
• Signs of liver disease or increased fluid pressure on the brain such as jaundice, dark urine, loss of appetite, persistent vomiting, persistent nausea, severe abdominal pain, severe stomach pain, unusual tiredness, persistent or severe headache or vision changes including blurred vision, double vision or decreased vision.
• Aches and pain in your bones or joints.
• Swelling or sudden weight gain.
• Signs of kidney problems such as a change in the amount of urine.
• Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

 What should I do if I miss a dose of Soriatane?

Skip the missed dose and take the next regularly scheduled dose.

What else is Soriatane called?

Soriatane is also known as Neotigason. Neotigason is not a generic alternative but the same brand name medication with a different name internationally. The generic alternative to Soriatane is known as acitretin.

How long does it take Soriatane to work?

It can take 2-3 months before your symptoms improve. Your psoriasis may get even worse when you start taking acitretin. Continue to take the medication as directed and tell your doctor if your symptoms do not improve.