1. Strength


2. Quantity

Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

What is Simbrinza?

Simbrinza is a medication used to treat high eye pressure for those with glaucoma or ocular hypertension. This medication works best for open-angle glaucoma. Simbrinza reduces the risk of vision loss, nerve damage, and blindness with those with high eye pressure. Simbrinza is a carbonic anhydrase inhibitor that works by decreasing the amount of fluid in the eye. Less fluid reduces the pressure in the eye and improves glaucoma symptoms.

Always read the medication instructions before using this medication.
Always follow your doctor’s directions.

  • Shake the bottle well before each dose and remove content lenses before using eye drops.
  • Do not touch the dropper tip to your eye
  • Tilt your head back and look upward, pulling down the lower lid to create a pouch. Hold the dropper above the eye and place a drop in the pouch.
  • Look downward and close your eyes, placing one finger at the corner of your eye near the nose.
  • Apply pressure to this area for one to two minutes
  • Repeat this step for the other eye
  • Do not rinse the dropper tip


Make sure to tell your doctor:

  • If you have any drug or other allergies.
  • If you regularly drink alcohol or consume marijuana products
  • If you take any other prescription or over-the-counter medications.
  • If you have a medical history of blood vessel diseases, heart disease, kidney disease, liver disease, or low blood pressure.
  • Your vision may become temporarily blurred after use, so do not drive or use machinery until you can do it safely.
  • If you are pregnant or planning on pregnancy.
  • If you are breast-feeding.

Side Effects of Simbrinza

Common side effects of Simbrinza:

  • Eye discomfort (itching, redness, and discharge)
  • Dry eyes
  • Feeling like something is in your eye
  • Dry mouth
  • Dry eyes
  • Bitter taste in your mouth
  • Dizziness
  • Drowsiness
  • Tiredness
  • Headache

If you have any of the following side effects, seek medical help:

  • Fainting
  • Slow or irregular heartbeat
  • Signs of an allergic reaction (swelling of the face, tongue, or throat)
  • Trouble breathing


How often should Simbrinza be used?

Always follow your doctor's instructions when starting a new medication. Generally. Simbrinza is used three times a day to prevent glaucoma. You cannot overdose on Simbrinza, but it is harmful if swallowed.

Can I use other eye drops if I’m using Simbrinza?

Yes! If you are using another kind of eye medication, wait at least 5 minutes after using Simbrinza to use your other eye drops.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1507 and a member of our CareTeam will be happy to assist you.

Call 1-877-204-1507
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

Great service, pricing and responsive
Lynne August 31, 2021

Real Customers, Honest Reviews

Excellent 1st time service!
Harry August 30, 2021

Real Customers, Honest Reviews

Excellent experience. Friendly, convenient and professional.
Patrick August 30, 2021

Real Customers, Honest Reviews

Great customer service and good value compared to drug cost here in the US
Patti Ann August 1, 2021

Real Customers, Honest Reviews

Canada Pharmacy Depot is truly one of the best and last places where I can experience truly customer-focused SERVICE! Your staff are always very professional, friendly, knowledgeable, and reliable. I am now old enough to remember when this sort of service was common in the United States. No longer. Thank you for not only providing excellent access to expensive prescriptions, but also a reminder that professionals DO still exist.
Valerie July 27, 2021

Real Customers, Honest Reviews

Very easy, smooth & financially worthwhile transaction. Will definitely return to reorder in a couple of months.
Stephen July 26, 2021

Real Customers, Honest Reviews

First time customer, a little hesitant. It worked out great. Big savings on script.
raymond July 16, 2021

Real Customers, Honest Reviews

I have been really pleased with the service I have gotten. Thank you for fabulous service and timely every time.
Nancy July 15, 2021

Real Customers, Honest Reviews

good price compared to US medication
christiane August 30, 2021

Real Customers, Honest Reviews

The customer service was really good, but I was very disappointed with how long it took to receive my medicine. Generally, when someone needs medicine, it is important that they get it pretty quick.
Faigy July 15, 2021
Read All Reviews
Write a Review

Get our newsletter

Health news and medication updates delivered right to your inbox.