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Canada Pharmacy Depot Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
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What is Simbrinza?

Simbrinza is a medication used to treat high eye pressure for those with glaucoma or ocular hypertension. This medication works best for open-angle glaucoma. Simbrinza reduces the risk of vision loss, nerve damage, and blindness with those with high eye pressure. Simbrinza is a carbonic anhydrase inhibitor that works by decreasing the amount of fluid in the eye. Less fluid reduces the pressure in the eye and improves glaucoma symptoms.

Always read the medication instructions before using this medication.
Always follow your doctor’s directions.

  • Shake the bottle well before each dose and remove content lenses before using eye drops.
  • Do not touch the dropper tip to your eye
  • Tilt your head back and look upward, pulling down the lower lid to create a pouch. Hold the dropper above the eye and place a drop in the pouch.
  • Look downward and close your eyes, placing one finger at the corner of your eye near the nose.
  • Apply pressure to this area for one to two minutes
  • Repeat this step for the other eye
  • Do not rinse the dropper tip

Cautions

Make sure to tell your doctor:

  • If you have any drug or other allergies.
  • If you regularly drink alcohol or consume marijuana products
  • If you take any other prescription or over-the-counter medications.
  • If you have a medical history of blood vessel diseases, heart disease, kidney disease, liver disease, or low blood pressure.
  • Your vision may become temporarily blurred after use, so do not drive or use machinery until you can do it safely.
  • If you are pregnant or planning on pregnancy.
  • If you are breast-feeding.

Side Effects of Simbrinza

Common side effects of Simbrinza:

  • Eye discomfort (itching, redness, and discharge)
  • Dry eyes
  • Feeling like something is in your eye
  • Dry mouth
  • Dry eyes
  • Bitter taste in your mouth
  • Dizziness
  • Drowsiness
  • Tiredness
  • Headache

If you have any of the following side effects, seek medical help:

  • Fainting
  • Slow or irregular heartbeat
  • Signs of an allergic reaction (swelling of the face, tongue, or throat)
  • Trouble breathing

FAQs

How often should Simbrinza be used?

Always follow your doctor's instructions when starting a new medication. Generally. Simbrinza is used three times a day to prevent glaucoma. You cannot overdose on Simbrinza, but it is harmful if swallowed.

Can I use other eye drops if I’m using Simbrinza?

Yes! If you are using another kind of eye medication, wait at least 5 minutes after using Simbrinza to use your other eye drops.

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Real Customers, Trustworthy Reviews

Read what others have to say before you buy — honest reviews from real people.

Everything was as expected with no problems. thank you.

VictorJuly 17, 2026

Karen is very good to work with and easy to understand.

KarenJuly 6, 2026

Always good, positive experience in obtaining my Pradaxa. This medication has now been discontinued by my provider because I have a watchman device now. Thank you for your care and service.

RobertJuly 2, 2026

It was nicely packaged. The price was amazing thank you so much. Looking forward to doing more business with you and passing the information on to others.

CarolJune 27, 2026

What a lifesaver the Canadian Pharmaceutical Depot is. My prescriptions cost me half of what I would pay in the United States. The product is as described and works as prescribed. The package was intact. Your customer service people have been amazing and answered all the questions I had. Thank you again for being available.

CarolJune 26, 2026

My prescription refill was simple and quick.

LanceJune 24, 2026

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1507 and a member of our CareTeam will be happy to assist you.

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* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.