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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
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Buy Retin-A Cream (Tretinoin Cream) Online

Canada Pharmacy Depot is a safe and affordable online pharmacy which makes ordering Canadian drugs such as Retin-A Cream hassle free while saving you up to 90% on the cost of your medication. Buy Retin-A Cream online today!

What is Retin-A Cream?

Retin-A Cream is a topical cream containing tretinoin which is used to treat acne by promoting the peeling of affected skin areas and unclogging pores. This affects the growth of skin cells which helps to decrease the severity and quantity of pimples and promotes the quick healing of pimples which do develop.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

  • Retin-A Cream should be applied at bedtime.
  • Thoroughly wash your hands and the affected skin with bland, mild soap and water. Wait 20 to 30 minutes before applying to make sure your skin is completely dry.
  • Use your fingertips to apply tretinoin cream to the affected areas. Only use enough cream to cover the affected area with a thin layer of medication.
  • Only apply Retin-A Cream to the affected area. Avoid getting this medication in your eyes, ears, mouth, corners along your nose or vaginal area.
  • Do not apply tretinoin cream to sunburned, cut, scraped or eczema-affected skin.
  • It may take between 8 to 12 weeks before you notice the results of this medication. Continue to use it regularly at the same time each day. Do not use more of this medication or use it more frequently than directed by your doctor.
  • Tell your doctor if your condition worsens or persists.

Cautions

Make sure to tell your doctor and pharmacist:

  • If you have any drug or other allergies.
  • Which other prescription and non-prescription medications you currently take.
  • Your medical history especially of eczema, actinic keratoses, skin cancer or any other skin conditions.
  • If you are pregnant, planning pregnancy or breast feeding.

Also be aware that:

  • Extreme cold, wind or other weather may be irritating.
  • Retin-A Cream may make your skin sensitive to sunlight or UV light. Avoid prolonged or unnecessary exposure to sunlight and wear protective clothing and sunscreen. Avoid tanning beds and sunlamps.

Side effects of Retin-A Cream

Common Retin-A Cream side effects may include but are not limited to:

  • A brief sensation of warmth or stinging after applying tretinoin.
  • Skin redness, itching, mild burning, dryness or scaling during the first 2-4 weeks of using this cream.

Contact your doctor if you experience any of the following side effects of tretinoin cream:

  • Blistering, crusting, swelling or burning of the skin.
  • Eye watering or redness.
  • Swelling of your eyelids.
  • Skin discoloration.
  • Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

FAQs

How long does Retin-A Cream take to work?

It may take between 8 to 12 weeks before you notice the results of this medication. Continue to use it regularly at the same time each day. Skin redness, itching, mild burning, dryness or scaling during the first 2-4 weeks of using this cream.

What else is Retin-A Cream called?

Retin-A Cream is also known as Retino A Cream. Retino A Cream is not a generic alternative but the same brand name medication with a different name internationally. The generic alternative to Retin-A Cream is known as Tretinoin Cream.

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Read what others have to say before you buy — honest reviews from real people.

We have had very good service from the Canada Pharmacy Depot, obtaining a very expensive medication (in the USA) for the very same medication from India for a fraction of the US cost ($488/3mo supply vs $1400/1mo supply). This has been a godsend bc my husband has Parkinson's Disease and takes many medications to manage his condition. It does take longer to get the medication, but you just have to plan ahead for significant savings.

JoyceJanuary 29, 2026

So nice and easy to order and arrange payment by phone...especially for this OLD person who is "computer resistive(illiterate)"

PeterJanuary 25, 2026

I called with the purpose of refilling my order. The person I interacted with was polite, careful, and efficient. Very well organized and fastidious about verifying the details of my order and payment.

CharlesJanuary 22, 2026

The Canadian Depot Pharmacy always updates me on my orders. Easy to use and a big cost savings.

DebbieJanuary 20, 2026

Outstanding customer service and courtesy. Thank you for helping to resolve my issue with my order for Eliquis.

DonnaJanuary 16, 2026

Always excellent and a pleasure!

JosephJanuary 15, 2026

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1507 and a member of our CareTeam will be happy to assist you.

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Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.