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Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

Buy Prempro Online

It has never been easier to buy your prescription medications online from Canadian pharmacies. Canada Pharmacy Depot lets you buy Prempro quickly and for a fraction of the cost you are used to paying in the US. Order online today or call us 7 days a week.

What is Prempro?

Prempro contains a combination of conjugated estrogens and medroxyprogesterone and is used to treat symptoms of menopause such as vaginal changes and hot flashes. Prempro can also be used to prevent osteoporosis in menopausal women. Estrogen is a female sex hormone that is naturally produced in the ovaries and is necessary for many body processes. Medroxyprogesterone is a form of progesterone which is a female hormone that is important for regulating menstruation and ovulation.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

  • Prempro should be taken at the same time each day. Your doctor may direct you to take Prempro alone or with other medications.
  • See your doctor for regular checks while taking Prempro.
  • Self-examine your breasts monthly and have regular mammograms.
  • Tell your doctor if you will be having major surgery or if you will be on long-term bed rest. You may need to temporarily stop taking Prempro.


Make sure to tell your doctor and pharmacist:

  • If you have any drug or other allergies.
  • Which other prescription and non-prescription medications you currently take.
  • Your medical history especially of unusual vaginal bleeding, liver disease, bleeding disorders, heart disease, heart attack, stroke, blood clots, cancer, high blood pressure, high cholesterol, hysterectomy, jaundice, kidney disease, gallbladder disease, asthma, epilepsy, migraines, lupus, endometriosis, uterine fibroid tumors, porphyria, thyroid disorder, high levels of calcium in your blood or diabetes.
  • Your family and personal history of angioedema.
  • If you will be having major surgery.
  • If you are overweight or if you smoke as these factors may increase your risk of blood clots, heart attack or stroke.
  • If you are breast feeding.

Also be aware that:

  • Prempro should not be used if you are pregnant.

Side effects of Prempro

Common Prempro side effects may include but are not limited to:

  • Stomach upset, nausea or vomiting.
  • Bloating or weight changes.
  • Breast tenderness.
  • Headaches.

Contact your doctor if you experience any of the following side effects of Prempro:

  • Mental or mood changes such as depression or memory loss.
  • Unusual vaginal bleeding such as spotting, breakthrough bleeding, prolonged or recurrent bleeding.
  • Breast lumps
  • New or increased vaginal itching, odor, discharge or irritation.
  • Severe stomach or abdominal pain.
  • Persistent vomiting or nausea.
  • Increased thirst or urination.
  • Jaundice.
  • Sudden or severe headaches.
  • Dark urine.
  • Swelling of the hands, ankles or feet.
  • Pain in your chest, jaw or left arm.
  • Unusual sweating.
  • Coughing up blood.
  • Sudden dizziness or fainting.
  • Confusion or slurred speech.
  • Pain, redness or swelling of the legs.
  • Sudden vision changes such as partial or complete blindness.
  • Tingling, numbness or weakness in the arms or legs.
  • Trouble breathing.
  • Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.


What should I do if I miss a dose of Prempro?

If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, then skip your missed dose.

What else is Prempro called?

Prempro is also known as Premique. Premique is not a generic alternative but the same brand name medication with a different name internationally.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1507 and a member of our CareTeam will be happy to assist you.

Call 1-877-204-1507
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

Hello, as a retired USA pharmacist, I can say that Canada Pharmacy Depot has 2 awesome points in my book. Number 1 is the saving cost. If I use my Medicare D plan, I'm into the "coverage gap" in January. It amazes me how over priced the USA system is, sad I have to say that, but it is totally true. Point Number 2 is your customer service. I used to try to go out of my way for patients. I'm definitely glad seeing the staff at Canada Pharmacy Depot embodies that same desire....KUDOS... Paul
Paul February 27, 2020

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I was very satisfied with the service and knowledge of your staff. Very professional and friendly. This was my first order and I felt very comfortable dealing with your pharmacy. I was walked through every step and my questions were answered.
Susan February 21, 2020

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I was very satisfied with your information about how to set up my account. Thanks!
Neoma February 21, 2020

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Wonderful service. Appreciate that you try to keep costs as low as you can.
Carolyn February 19, 2020

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Once the details were done setting up the account, the follow up on keeping me posted on the order was excellent. The prescription came well within the expected delivery date. Will be following up shortly for my refill.
Roslyn February 19, 2020

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I have not yet received the meds yet, but so far my experience with your reps has been fantastic! Very smart, very friendly and understanding. She was a great representative who explained the details and put my mind at ease.
Barbara February 18, 2020

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My order arrived today...love you guys. I have a serious illness and because of your ability to get my medicine to me for a price that I can afford...I'm alive and love ALL Canadians!
George February 18, 2020

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Your commitment is awesome.....thank you
Barbara February 11, 2020

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I have not used the Canada Pharmacy Depot prior to this order. I was pleased that you did a price match and the order was managed quickly and efficiently after providing the necessary prescription. I will use the CPD again! Don
Donald January 30, 2020

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The Canada Pharmacy Depot exceeded my expectations. They made it easy to send them the Rx and the wait time was not long before my order arrived.
ROBERT October 20, 2019
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