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What is Pentasa?

Pentasa is a medication used to treat the bowel diseases ulcerative colitis and Crohn disease and to prevent their symptoms from recurring. Pentasa contains mesalamine which works by decreasing the swelling within the colon. Taking mesalamine may help to reduce symptoms including stomach pain, rectal bleeding and diarrhea.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

• Pentasa may be taken with or without food.
• Swallow mesalamine capsules whole without chewing, crushing or breaking them. If you struggle to swallow this medication whole, you may open the capsule and sprinkle the contents onto yoghurt or applesauce and eaten immediately without chewing.
• Speak to your doctor if your symptoms do not improve.

Make sure to tell your doctor and pharmacist:

• If you have any drug or other allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history especially of heart disease, kidney disease, liver disease, stomach blockage, intestinal blockage or pyloric stenosis.
• If you are pregnant, planning on pregnancy or breast feeding.

Also be aware that:

• Pentasa may cause unusual test results. Tell any medical testing personnel that you are taking mesalamine.

Common Pentasa side effects may include but are not limited to:

• Nausea, vomiting or diarrhea.
• Headaches.

Contact your doctor if you experience any of the following side effects of mesalamine:

• Worsened symptoms such as bloody diarrhea, fever, increased cramping or increased abdominal pain.
• Changes to your amount of urine as this may be a sign of kidney problems.
• Chest pain.
• Dark urine.
• Persistent nausea or vomiting.
• Shortness of breath.
• Severe stomach or abdominal pain.
• Jaundice.
• Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

What should I do if I miss a dose of Pentasa?

If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, then skip your missed dose.

Does Pentasa have a generic alternative?

There is currently no therapeutically equivalent generic alternative to Pentasa 500mg.