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What is Kazano?

Kazano is a combination medication containing alogliptin and metformin used to help control blood sugar levels in adults with type 2 diabetes. The two medications work together. Alogliptin works by regulating the levels of insulin that your body produces after eating while metformin decreases the glucose production in your liver and the absorption of glucose by the intestines. Kazano should be used alongside diet and exercise to treat type 2 diabetes and should not be used to treat type 1 diabetes.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

• Kazano is taken orally with food and is typically taken twice daily.
• You should drink plenty of fluids while taking this medication.
• Your Kazano dosage is based on your medical condition, other medications you may be taking and your response to treatment. Your doctor may start your medication on a low dose and gradually increase this to reduce the risk of side effects.
• Check your blood sugar level regularly and keep a track of your results. Your medication may need to be adjusted.
• Kazano is most effective when it is taken regularly. Try to take this medication at the same time each day. Tell your doctor if your condition does not improve or worsens.
• Follow your diabetes management plan including medication, diet and exercise.

Make sure to tell your doctor and pharmacist:

• If you have any drug or other allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history especially of breathing problems, kidney disease, liver problems, pancreas disease, gallstones or a vitamin B12 deficiency.
• If you are breast feeding.

Also be aware that:

• This medication may make you dizzy, drowsy or blur your vision. Do not drive, operate machinery or do anything else requiring alertness or clear vision until it can be done safely.
• Limit your alcohol intake while taking this medication as it can increase the risk of low blood sugar or lactic acidosis.
• You may need to stop taking this medication for a short time before surgery or a medical procedure. Tell all of your doctors or dentists that you take Kazano.
• You should drink plenty of fluids while taking this medication to prevent dehydration.
• When your body is stressed such as due to fever, infection or surgery, it may be harder to control your blood sugar. Tell your doctor as your treatment may need to be changed.
• Older adults may be more sensitive to the side effects of this medication.
• Kazano can cause changes to a woman’s menstrual cycle, increasing the chance of pregnancy. Use reliable birth control while taking this medication.
• This medication should only be used when clearly needed during pregnancy. Your doctor may need to change your treatment plan during pregnancy.

Common Kazano side effects may include but are not limited to:

• Diarrhea or upset stomach.
• Headache or back pain.
• Cold symptoms such as stuffy nose, sore throat or sinus pain.
• Signs of increased blood pressure such as blurred vision, severe headache or a pounding the neck or ears.

Contact your doctor if you experience any of the following side effects of Kazano:

• Signs of lactic acidosis such as unusual muscle pain, coldness, breathing problems, dizziness, lightheadedness, tiredness, stomach pain, vomiting, weakness or a slow or irregular heartbeat. Seek emergency medical help even if these symptoms are mild.
• Signs of a severe skin reaction such as fever, burning eyes, skin pain, sore throat or a red or purple skin rash which blisters or peels.
• Signs of pancreatitis such as nausea, vomiting, loss of appetite, fast heartbeats or a sever pain in the upper stomach which spreads to your back.
• Severe or ongoing joint pain.
• Painful or burning urination.
• Signs of liver problems such as nausea, loss of appetite, jaundice, dark urine, upper stomach pain or tiredness.
• Signs of heart failure such as rapid weight gain, swelling in your legs or feet or shortness of breath, even while lying down.
• Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

What should I do if I miss a dose of Kazano?

If you miss a dose of this medication, take it with food as soon as you remember. If it is almost time for your next dose, then skip your missed dose. Do not take two doses at once.

What else is Kazano called?

Kazano is also known as Nesina Met or Vipdomet. Nesina Met and Vipdomet are not a generic alternatives but the same brand name medication with different names internationally.