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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

Buy Estrace (Estradiol) Online

Are you looking to buy Estrace and other prescription medications for a fraction of what you usually pay? Buying medications with Canada Pharmacy Depot can save you up to 90% on the cost of Estrace. It’s safe, convenient and quick from our reputable Canadian pharmacy and you can order online or call us 7 days a week.

What is Estrace?

Estrace tablets and the generic alternative estradiol are medications used to treat vaginal changes, hot flashes and other menopausal symptoms caused by the body producing less estrogen. Estrace may also be used to prevent osteoporosis in menopausal women and to replace estrogen in women who have conditions which cause a lack of natural estrogen in the body such as ovarian failure. Estradiol is a female sex hormone which regulates many body processes.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

  • Take Estrace by mouth. Taking Estrace tablets with food or after a meal can help to prevent stomach upset.
  • Your doctor may want to check your progress on a regular basis.
  • While taking Estrace, you should check your breasts for lumps on a monthly basis and have an annual mammogram.


Make sure to tell your doctor and pharmacist:

  • If you have any drug or other allergies.
  • Which other prescription and non-prescription medications you currently take.
  • Your medical history especially of unusual vaginal bleeding, liver disease, liver problems, heart attack, heart disease, heart problems, stroke, blood clot, blood disorders, cancer, jaundice, kidney disease, gallbladder disease, asthma, epilepsy or other seizure disorders, migraines, lupus endometriosis, uterine fibroid tumors, porphyria, high blood pressure, high cholesterol, diabetes, thyroid disorders or high levels of calcium in your blood.
  • If you have personal or family history of angioedema.
  • If you smoke or if you are overweight.
  • If you are breast feeding.

Also be aware that:

  • Estrace should not be used if you are pregnant.

Side effects of Estrace

Common Estrace side effects may include but are not limited to:

  • Diarrhea, vomiting, nausea or stomach cramps.
  • Changes to menstrual periods, vaginal itching, discharge or breakthrough bleeding.
  • Cold symptoms including stuffy nose, sore throat or sinus pain.
  • Sleep problems.
  • Mood changes.
  • Weight gain.
  • Headache, back pain or breast pain.
  • Thinning scalp hair.

Contact your doctor if you experience any of the following side effects of Estrace:

  • Stomach swelling or tenderness.
  • Breast lumps.
  • Unusual vaginal bleeding or pelvic pain.
  • Jaundice.
  • Memory problems, confusion or unusual behavior.
  • Symptoms of a heart attack such as chest pain or pressure, nausea, sweating, or pain spreading to your jaw or shoulder.
  • Symptoms of a stroke such as severe headache, slurred speech, problems with vision or balance, or sudden numbness or weakness especially on one side of the body.
  • Symptoms of a blood clot such as sudden vision loss, stabbing chest pain, shortness of breath, coughing up blood or pain or warmth in one or both legs.
  • Symptoms of high levels of calcium such as nausea, constipation, vomiting, increased urination or thirst, muscle weakness, lack of energy or bone pain.
  • Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.


What should I do if I miss a dose of Estrace?

If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, then skip your missed dose.

What should I avoid while taking Estrace?

Avoid eating grapefruit and drinking grapefruit juice as they can lead to unwanted side effects. Avoid smoking as it can greatly increase your risk of blood clots, stroke and heart attack.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1507 and a member of our CareTeam will be happy to assist you.

Call 1-877-204-1507
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

Great service, pricing and responsive
Lynne August 31, 2021

Real Customers, Honest Reviews

Excellent 1st time service!
Harry August 30, 2021

Real Customers, Honest Reviews

Excellent experience. Friendly, convenient and professional.
Patrick August 30, 2021

Real Customers, Honest Reviews

Great customer service and good value compared to drug cost here in the US
Patti Ann August 1, 2021

Real Customers, Honest Reviews

Canada Pharmacy Depot is truly one of the best and last places where I can experience truly customer-focused SERVICE! Your staff are always very professional, friendly, knowledgeable, and reliable. I am now old enough to remember when this sort of service was common in the United States. No longer. Thank you for not only providing excellent access to expensive prescriptions, but also a reminder that professionals DO still exist.
Valerie July 27, 2021

Real Customers, Honest Reviews

Very easy, smooth & financially worthwhile transaction. Will definitely return to reorder in a couple of months.
Stephen July 26, 2021

Real Customers, Honest Reviews

First time customer, a little hesitant. It worked out great. Big savings on script.
raymond July 16, 2021

Real Customers, Honest Reviews

I have been really pleased with the service I have gotten. Thank you for fabulous service and timely every time.
Nancy July 15, 2021

Real Customers, Honest Reviews

good price compared to US medication
christiane August 30, 2021

Real Customers, Honest Reviews

The customer service was really good, but I was very disappointed with how long it took to receive my medicine. Generally, when someone needs medicine, it is important that they get it pretty quick.
Faigy July 15, 2021
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