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Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

Buy Estrace (Estradiol) Online

Are you looking to buy Estrace and other prescription medications for a fraction of what you usually pay? Buying medications with Canada Pharmacy Depot can save you up to 90% on the cost of Estrace. It’s safe, convenient and quick from our reputable Canadian pharmacy and you can order online or call us 7 days a week.

What is Estrace?

Estrace tablets and the generic alternative estradiol are medications used to treat vaginal changes, hot flashes and other menopausal symptoms caused by the body producing less estrogen. Estrace may also be used to prevent osteoporosis in menopausal women and to replace estrogen in women who have conditions which cause a lack of natural estrogen in the body such as ovarian failure. Estradiol is a female sex hormone which regulates many body processes.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

  • Take Estrace by mouth. Taking Estrace tablets with food or after a meal can help to prevent stomach upset.
  • Your doctor may want to check your progress on a regular basis.
  • While taking Estrace, you should check your breasts for lumps on a monthly basis and have an annual mammogram.


Make sure to tell your doctor and pharmacist:

  • If you have any drug or other allergies.
  • Which other prescription and non-prescription medications you currently take.
  • Your medical history especially of unusual vaginal bleeding, liver disease, liver problems, heart attack, heart disease, heart problems, stroke, blood clot, blood disorders, cancer, jaundice, kidney disease, gallbladder disease, asthma, epilepsy or other seizure disorders, migraines, lupus endometriosis, uterine fibroid tumors, porphyria, high blood pressure, high cholesterol, diabetes, thyroid disorders or high levels of calcium in your blood.
  • If you have personal or family history of angioedema.
  • If you smoke or if you are overweight.
  • If you are breast feeding.

Also be aware that:

  • Estrace should not be used if you are pregnant.

Side effects of Estrace

Common Estrace side effects may include but are not limited to:

  • Diarrhea, vomiting, nausea or stomach cramps.
  • Changes to menstrual periods, vaginal itching, discharge or breakthrough bleeding.
  • Cold symptoms including stuffy nose, sore throat or sinus pain.
  • Sleep problems.
  • Mood changes.
  • Weight gain.
  • Headache, back pain or breast pain.
  • Thinning scalp hair.

Contact your doctor if you experience any of the following side effects of Estrace:

  • Stomach swelling or tenderness.
  • Breast lumps.
  • Unusual vaginal bleeding or pelvic pain.
  • Jaundice.
  • Memory problems, confusion or unusual behavior.
  • Symptoms of a heart attack such as chest pain or pressure, nausea, sweating, or pain spreading to your jaw or shoulder.
  • Symptoms of a stroke such as severe headache, slurred speech, problems with vision or balance, or sudden numbness or weakness especially on one side of the body.
  • Symptoms of a blood clot such as sudden vision loss, stabbing chest pain, shortness of breath, coughing up blood or pain or warmth in one or both legs.
  • Symptoms of high levels of calcium such as nausea, constipation, vomiting, increased urination or thirst, muscle weakness, lack of energy or bone pain.
  • Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.


What should I do if I miss a dose of Estrace?

If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, then skip your missed dose.

What should I avoid while taking Estrace?

Avoid eating grapefruit and drinking grapefruit juice as they can lead to unwanted side effects. Avoid smoking as it can greatly increase your risk of blood clots, stroke and heart attack.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1507 and a member of our CareTeam will be happy to assist you.

Call 1-877-204-1507
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

I love Canada pharmacy Depot! they are very professional and friendly. The prices are amazing.
Maria February 5, 2021

Real Customers, Honest Reviews

Hello, as a retired USA pharmacist, I can say that Canada Pharmacy Depot has 2 awesome points in my book. Number 1 is the saving cost. If I use my Medicare D plan, I'm into the "coverage gap" in January. It amazes me how over priced the USA system is, sad I have to say that, but it is totally true. Point Number 2 is your customer service. I used to try to go out of my way for patients. I'm definitely glad seeing the staff at Canada Pharmacy Depot embodies that same desire....KUDOS... Paul
Paul February 27, 2020

Real Customers, Honest Reviews

I was very satisfied with the service and knowledge of your staff. Very professional and friendly. This was my first order and I felt very comfortable dealing with your pharmacy. I was walked through every step and my questions were answered.
Susan February 21, 2020

Real Customers, Honest Reviews

I was very satisfied with your information about how to set up my account. Thanks!
Neoma February 21, 2020

Real Customers, Honest Reviews

Wonderful service. Appreciate that you try to keep costs as low as you can.
Carolyn February 19, 2020

Real Customers, Honest Reviews

Once the details were done setting up the account, the follow up on keeping me posted on the order was excellent. The prescription came well within the expected delivery date. Will be following up shortly for my refill.
Roslyn February 19, 2020

Real Customers, Honest Reviews

I have not yet received the meds yet, but so far my experience with your reps has been fantastic! Very smart, very friendly and understanding. She was a great representative who explained the details and put my mind at ease.
Barbara February 18, 2020

Real Customers, Honest Reviews

My order arrived today...love you guys. I have a serious illness and because of your ability to get my medicine to me for a price that I can afford...I'm alive and love ALL Canadians!
George February 18, 2020

Real Customers, Honest Reviews

I have not used the Canada Pharmacy Depot prior to this order. I was pleased that you did a price match and the order was managed quickly and efficiently after providing the necessary prescription. I will use the CPD again! Don
Donald January 30, 2020

Real Customers, Honest Reviews

The Canada Pharmacy Depot exceeded my expectations. They made it easy to send them the Rx and the wait time was not long before my order arrived.
ROBERT October 20, 2019
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