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What is Triamterene/HCTZ?

Triamterene/HCTZ is a combination medicine used to treat fluid retention and high blood pressure (hypertension). It is usually given to people in whom other diuretics have caused hypokalemia (low potassium levels in your blood).

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Your doctor may occasionally change your dose.
Triamterene/HCTZ  is usually taken once per day.
You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.


Your heart function may also need to be checked using an electrocardiograph or ECG (sometimes called an EKG). Severe illness can affect your potassium levels. 


If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Triamterene/HCTZ Cautions

Before taking Triamterene/HCTZ, tell your doctor or pharmacist your medical history, especially of: diabetes, gout, high level of potassium in the blood, kidney disease (including kidney stones), liver disease, lupus, skin cancer. Additionally, if you are allergic to triamterene or hydrochlorothiazide; or if you have any other allergies.

Triamterene/HCTZ Side Effects

 Common side effects of Triamterene/HCTZ may include:

  • stomach pain, nausea, diarrhea, constipation;
  • dizziness, headache;
  • blurred vision; or
  • dry mouth.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects.

Get emergency medical help if you have signs of an allergic reaction (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction.

FAQs

What is Triamterene/HCTZ ?

Triamterene/HCTZ works primarily by lowering your blood pressure to the normal range and thus, in turn, preventing you from suffering a stroke, heart attack or kidney problems. It amalgamates two water pills within itself, namely, triamterene and hydrochlorothiazide. Combining these two particular white pills in Triamterene helps people who are taking this medicine urinate more. It leads to your body getting rid of excess salt and water.

Can you drink alcohol while taking Triamterene/HCTZ ?

Triamterene/HCTZ may make you dizzy. Alcohol or marijuana (cannabis) can make you dizzier. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

What are Triamterene/HCTZ side effects?

Dizziness, lightheadedness, headache, or upset stomach may occur as your body adjusts to the medication. 

 

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VictorJuly 17, 2026

Karen is very good to work with and easy to understand.

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Always good, positive experience in obtaining my Pradaxa. This medication has now been discontinued by my provider because I have a watchman device now. Thank you for your care and service.

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It was nicely packaged. The price was amazing thank you so much. Looking forward to doing more business with you and passing the information on to others.

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What a lifesaver the Canadian Pharmaceutical Depot is. My prescriptions cost me half of what I would pay in the United States. The product is as described and works as prescribed. The package was intact. Your customer service people have been amazing and answered all the questions I had. Thank you again for being available.

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A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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