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What is Differin XP Gel?

Differin XP Gel is used to treat acne. It works partly by keeping skin pores clear and stopping pimples from forming under the skin's surface.

Differin XP Gel will be different for different patients. Follow your doctor's directions on the label. The following information includes only the average doses of this medicine. 

For topical dosage form (gel) for acne:

  • Adults and teenagers—Apply a small amount as a thin film once a day, at least one hour before bedtime. Apply the medicine to dry, clean areas affected by acne. Rub in gently and well.
  • Please wash your hands afterward to remove any medicine that may remain on them.

To help clear up your acne completely, you must keep using Differin XP Gel for full-time treatment, even if your symptoms begin to clear up after a short time. If you stop using Differin XP Gel too soon, your acne may return or worsen.

Before taking Differin XP Gel

Before using Differin XP Gel, tell your doctor or pharmacist your medical history, especially of: eczema. If you are allergic to it, vitamin A-related drugs, or if you have any other allergies.

Weather extremes such as wind or cold may also irritate the skin. Use sunscreen daily and wear protective clothing when outdoors. Differin XP Gel may make you more sensitive to the sun. Before using Differin XP Gel, wait until your skin has completely recovered from a sunburn. Tell your doctor immediately if you get sunburned or have skin blisters/redness.

Avoid electrolysis, waxing and chemical depilatories for hair removal on the treated areas while using Differin XP Gel.

Differin XP Gel Side Effects

A brief sensation of warmth or stinging may occur right after applying the Differin XP Gel. Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using Differin XP Gel. These effects usually decrease with continued use. 

Tell your doctor immediately if you have any serious side effects, including very red/irritated skin, an intense burning sensation, eye redness and watering (conjunctivitis), eyelid swelling, and skin discoloration.

It is not a complete list of possible side effects. Contact your doctor or pharmacist if you notice other effects not listed above.

FAQs

What happens if you miss a dose of Differin XP Gel?

Apply the Differin XP Gel as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not apply extra medicine to make up for the missed dose.

What happens if you overdose on Differin XP Gel?

Seek emergency medical attention if you have used too much Differin XP Gel. Overdose symptoms may include skin redness, scaling, or irritation.

What should you avoid while using Differin XP Gel?

Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Differin XP Gel can make you sunburn more easily. 

Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid.

What potential Differin XP Gel side effects are there?

If you apply Differin XP Gel once daily, common side effects include dry skin, skin pain, pruritus, desquamation, and sunburn.

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