Anusol HC Ointment is used with other medications to treat proctitis and ulcerative colitis. It works by activating natural substances in the skin to reduce swelling, redness, and itching. It also relieves itching and swelling from hemorrhoids and other rectal problems.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the Anusol HC ointment exactly as directed. To apply the product to the outside of the anus only, use your finger to apply a small amount of ointment to the affected area and rub it gently.
Do not cover the area with plastic or waterproof bandages unless directed to do so by your doctor.
Wash hands immediately after use. Avoid getting the product in your eyes, nose, ears or mouth. If the medication gets in these areas, rinse the area immediately with clean water.

Dosage is based on your medical condition and response to therapy. Anusol HC ointment is usually used 2 to 4 times daily, after each bowel movement or as directed by your doctor. To help you remember, use it at the same times each day. Some conditions may become worse when this drug is suddenly stopped. Inform your doctor if your condition does not improve or worsens after 1 to 2 weeks.

Before using Anusol HC ointment, tell your doctor and pharmacist:

• If you are allergic to it or other medications,
• Many other medications may also interact with hydrocortisone. Be sure to tell your doctor about all the medications you are taking,
• If you have a fungal infection, peritonitis, intestinal obstruction, a fistula or a tear in the wall of your stomach or intestine,
• If you have or have ever had threadworms, diabetes; diverticulitis; heart failure; high blood pressure; a recent heart attack; osteoporosis, myasthenia gravis; emotional problems, depression or other types of mental illness; tuberculosis, ulcers; cirrhosis; or liver, kidney, or thyroid disease,
• If you have any untreated bacterial, parasitic, or viral infection anywhere in your body or a herpes eye infection,
• If you are pregnant, plan to become pregnant, or are breastfeeding. 
• If you are having surgery, including dental surgery,
• You should know that Anusol HC ointment may decrease your ability to fight infection and may prevent you from developing symptoms if you get an infection. Stay away from people who are sick, and wash your hands often while using this medication. 

Anusol-HC ointment may cause serious side effects. Call your doctor at once if you have the following:

• severe rectal pain or burning, bleeding from your rectum;
• new or worsening rectal irritation;
• fever or other signs of infection; or
• severe headaches, ringing in your ears, and pain behind your eyes.

Common side effects of Anusol-HC ointment may include:

• rectal itching, burning, or other irritation; or
• dryness or skin changes around the rectum.

These are not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects.

What should you know about the storage of Anusol-HC ointment?

Keep Anusol-HC ointment in the container it came in, tightly closed, and out of reach of children. Store it according to the package instructions. Store it at room temperature and away from excess heat and moisture. Do not freeze or refrigerate rectal hydrocortisone products.

What happens if you overdose on Anusol-HC ointment?

In case of overdose, If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services.

What are the possible side effects of Anusol HC Ointment?

• Rectal itching, or other irritation; or
• Skin changes around the rectum may occur.