Protopic Ointment is used on the skin to treat moderate to severe atopic dermatitis (itching, redness, and inflammation) in patients who have received other medicines that have not worked well. It helps to suppress these symptoms, which are reactions caused by the body's immune system. This medicine is available only with your doctor's prescription.

Use Protopic Ointment exactly as directed by your doctor. This medicine is for use on the skin only. Please do not get it in your eyes, nose, or mouth. Do not use on skin areas that have cuts or scrapes. If it does get on these areas, rinse it off right away. To use:

• Wash your hands with soap and water before and after using this medicine. If treating a rash on your hands, do not wash your hands after using the medicine.
• Dry the skin completely before applying the ointment.
• Apply a thin layer of ointment and rub it well to cover the affected areas.
• Do not cover the treated skin with occlusive dressings, bandages, or wraps.
• Do not bathe, shower, or swim right after applying for this medicine. 
• If your doctor recommends a moisturizer, apply it after applying for this medicine.
• Do not use cosmetics or other skin care products on the treated skin areas.

Before using Protopic Ointment, tell your doctor or pharmacist your medical history, especially of: swollen lymph nodes, use of light therapy (such as UVA or UVB), skin or other cancers, skin infections, other skin conditions, and kidney disease, and if you are allergic to it, other macrolide medications, or any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor. Consult your doctor before breastfeeding.

Get emergency medical help if you have signs of an allergic reaction to Protopic Ointment:

• Severe pain, burning, itching, or stinging;
• New or worsened skin symptoms;
• A mole that has changed in size or color; or
• Symptoms of viral skin infection - cold sores around your mouth, skin sores or blisters, scabs, itching, and tingling.

Common Protopic Ointment side effects may include:

• Burning, stinging, itching, or tingling of treated skin,
• Viral skin infection;
• Skin is more sensitive to hot or cold temperatures;
• Acne, redness or crusting around your hair follicles;
• Upset stomach;
• Headache, muscle pain;
• Runny or stuffy nose; or
• Fever, chills, body aches, sore throat, cough, swollen glands.

What are the possible side effects Protopic Ointment can cause?

Protopic Ointment may be associated with an increased risk of developing chicken pox, eczema herpeticum, herpes simplex virus infections, or varicella-zoster virus infection. 

Is it safe to have alcohol while on Protopic Ointment?

Limit alcoholic beverages. This drug may make you more sensitive to the effects of alcohol. Your face or skin may flush red and feel hot.

Does Protopic Ointment cause skin sensitivity?

Protopic Ointment may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.