Comparing Erectile Dysfunction Drugs

Tuesday 25 May 2021
Erectile Dysfunction
4 minute(s) read

Table of Contents


I. How ED Medications Work 

II. Differences in Longevity 

III. Differences in Strength 

IV. Differences in Side Effects 

V. What's the Consensus?


There are several drugs out there like Cialis, generic Viagra, and Levitra that can improve ED symptoms, but what’s the difference between these drugs? It is important to have a good understanding of erectile dysfunction before jumping into a treatment plan. Read on to learn more about Canadian Cialis different types of erectile dysfunction medications available.

How does Erectile Dysfunction Medication Work? 

An erection is caused by the engorgement of the penis with blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide activates an enzyme that causes the production of cyclic guanosine monophosphate (cGMP). This enzyme is responsible for the amount of blood that the vessels deliver and remove from the penis.

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All ED medications are PDE5 inhibitors (phosphodiesterase). After ejaculation, PDE5 ends the erection process by breaking down a substance called cGMP (cyclic guanosine monophosphate). Once cGMP is broken down, the blood leaves the penis and the erection subsides. PDE5 inhibitors prevent this breakdown process and keeps the penis erect for longer.

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Differences in Longevity

Some people may prefer Cialis over other ED medications because it can be taken daily, meaning a consistent concentration of tadalafil in the body so you are ready for sexual activity at any time. Generic Cialis also comes with as-needed options, which are stronger dosages taken at least 30 minutes before sex. As-needed Cialis reaches peak concentration and effect two hours after taking but can last for up to 36 hours.

Viagra and Levitra do not stay in the system as long as Cialis and only last for about 4 to 6 hours. This is beneficial for some if a man only wants to take ED drugs as needed for sexual intercourse. Sildenafil and vardenafil are rapidly absorbed, so it takes about an hour to reach the maximal concentration of this drug.

Differences in Strength 

As mentioned above, Cialis is available at lower strengths to allow for daily dosing. At Canada Pharmacy Depot, Cialis is available at 2.5 mg, 5 mg, 10mg, and 20 mg dosage strengths. It is important to note that dosages of Cialis vary depending on a man’s health condition. The dosage may need to be reduced if kidney or liver disease is present.

Viagra is available in 25 mg, 50 mg, and 100 mg tablets. Levitra comes in 5 mg, 10 mg, or 20 mg dosages. Based on your treatment goals and factors such as your underlying health conditions, your doctor will determine which dosage strength is right for you. 

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Side Effects of ED Drugs

Some possible side effects of Cialis can include:

  • Headache, back pain, nasal congestion, and flushing
  • A possible drop in blood pressure, muscle or limb pain, or conjunctivitis
  • Hearing loss or painful erections lasting longer than four to six hours

Some side effects of Viagra can include:

  • Nausea
  • Dizziness
  • Rash
  • Urinary tract infections
  • Facial flushing
  • Headaches
  • Possible vision changes and color perception
  • Priapism (an erection that lasts more than 4 hours) [1]

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Levitra is used when needed, and, like Viagra, it is advised not to take this medicine more than once a day. A man should allow 24 hours to pass between doses. It is important to pay attention to any side effects, including:

  • Painful erection that lasts longer than 4 hours
  • Heart attack symptoms (chest pain, nausea, sweating, pain in the jaw or shoulder)
  • Stuffy nose
  • Upset stomach
  • Back pain
  • Flushing

Nitrate medications should be avoided to prevent dangerous drug interactions. In general, Levitra has fewer side effects than Viagra. Vision changes are considered a common side effect of Viagra, but changes to color perception are only a rare side effect of Levitra. [2]

What's the Best ED Pill?

Every medication has its pros and cons. Once you learn how to talk to your doctor about ED, they will help determine which drug is best. A physician will consider a man’s age, weight, and pre-existing health issues to determine the most effective erectile dysfunction drug. No matter what a man decides, Canada Pharmacy Depot is the place to buy Viagra and Cialis medications at a discounted cost.

When you use Canada Pharmacy Depot, you can save time and money through our online pharmacy. You will never have to go to a physical pharmacy again because we send all of your treatment drugs directly to your door. Visit our site to learn more today.

The content in this article is intended for informational purposes only. This website does not provide medical advice. In all circumstances, you should always seek the advice of your physician and/or other qualified health professionals(s) for drug, medical condition, or treatment advice. The content provided on this website is not a substitute for professional medical advice, diagnosis or treatment.

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